CLOVES syndrome
MeSH: C567863ORPHA: 140944
Overview
CLOVE syndrome is characterized by Congenital Lipomatous Overgrowth, progressive, complex and mixed truncal Vascular malformations, and Epidermal nevi
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with CLOVES syndrome, sourced from HPO and Orphanet clinical annotations.
Increased adipose tissueCapillary malformationFacial asymmetryBroad palmHemihypertrophyBulbous tips of toesSandal gapScoliosisMacrodactylyUlnar deviation of the handEpidermal nevusVenous malformationAsymmetric growthAbnormal lymphatic vessel morphologyHyperplasia of the maxillaRenal cystDental malocclusionPectus excavatumCutis marmorataIntellectual disabilitySeizureGait disturbanceAbnormal thrombosisPolymicrogyriaSpina bifidaMeningoceleMyelomeningocelePatellar dislocationHemimegalencephalyLower limb muscle weaknessAplasia/Hypoplasia of the corpus callosumRenal hypoplasia/aplasiaPolydactylySkin tagsPainCutaneous syndactylyTesticular lipomatosisSeborrheic keratosisAcral overgrowthArteriovenous malformationLower limb asymmetryHip dysplasiaNephroblastoma
Classification & Codes
MeSH Code
C567863Orphanet Code
ORPHA:140944CLOVES syndrome
| MeSH | C567863 |
| Orphanet | ORPHA:140944 |
| Treatments | 0 drug(s) |
| Symptoms on record | 43 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO