Cobb syndrome
ORPHA: 537212 Treatments Available
Overview
disease
Available Treatments (2)
| Drug | Form | Status | Countries | Lead Time |
|---|---|---|---|---|
| sirolimus Orphan | Oral tablet 0.5mg/1mg/2mg, oral solution 1mg/mL | FDA Approved, EMA Approved | 13 | 5d |
| bevacizumab Cold Chain | IV infusion, 25 mg/mL solution; intravitreal injection (off-label) | FDA Approved, EMA Approved | 12 | 14d |
Clinical Presentation
Signs and symptoms associated with Cobb syndrome, sourced from HPO and Orphanet clinical annotations.
Abnormality of the kidneySensory neuropathyAbnormality of the vertebral columnAngiokeratomaNevus flammeusHyperreflexiaCongestive heart failureAbnormal spinal cord morphologyParaparesisSpinal arteriovenous malformationBone painKyphoscoliosisArthralgiaUrinary bladder sphincter dysfunctionCutaneous angiolipomasFatigueArteriovenous malformationGangreneVisceral angiomatosisLymphangioma
Classification & Codes
Orphanet Code
ORPHA:53721Cobb syndrome
| Orphanet | ORPHA:53721 |
| Treatments | 2 drug(s) |
| Symptoms on record | 20 signs |
| Status | published |
Treatment Summary
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO