Cogan syndrome

MeSH: D055952ORPHA: 1467

Overview

a rare vasculitis of children and young adults characterized by nonsyphilitic interstitial keratitis of cornea, fever and fatigue.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Cogan syndrome, sourced from HPO and Orphanet clinical annotations.

TinnitusKeratitisPhotophobiaAbnormal vestibular functionVertigoReduced visual acuitySensorineural hearing impairmentThrombocytosisAnemiaIncreased total leukocyte countElevated erythrocyte sedimentation rateInflammatory abnormality of the eyeConjunctivitisUveitisBlindnessAortic regurgitationVasculitisLarge vessel vasculitisScleritisEpiscleritis

Classification & Codes

MeSH Code

D055952

Orphanet Code

ORPHA:1467
Cogan syndrome
MeSHD055952
OrphanetORPHA:1467
Treatments0 drug(s)
Symptoms on record20 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
Cogan syndrome | OrphanDrug