combined immunodeficiency due to CRAC channel dysfunction

ORPHA: 169090

Overview

deficiency (see these terms)

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with combined immunodeficiency due to CRAC channel dysfunction, sourced from HPO and Orphanet clinical annotations.

Chronic otitis mediaAmelogenesis imperfectaHypotoniaMeningitisFeverPneumoniaRecurrent bacterial infectionsImmunodeficiencyRecurrent fungal infectionsAutoimmunityMyopathyRecurrent viral infectionsHypoplasia of the irisHypocalcification of dental enamelRecurrent mycobacterial infectionsSepsisAnhidrosisSplenomegalyHepatomegalyLymphadenopathyThrombocytopeniaHemolytic anemiaNeoplasm

Classification & Codes

Orphanet Code

ORPHA:169090
combined immunodeficiency due to CRAC channel dysfunction
OrphanetORPHA:169090
Treatments0 drug(s)
Symptoms on record23 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO