combined vitamin K-dependent clotting factors deficiency
MeSH: C564741ORPHA: 98434
Available Treatments (0)
No treatments linked yet
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Clinical Presentation
Signs and symptoms associated with combined vitamin K-dependent clotting factors deficiency, sourced from HPO and Orphanet clinical annotations.
AtherosclerosisHypoplasia of the nasal boneJoint hemorrhageShortening of all distal phalanges of the fingersEpiphyseal stipplingProlonged bleeding following procedurePost-partum hemorrhageCephalohematomaProlonged bleeding following circumcisionEcchymosisVentricular septal defectAtrial septal defectGastrointestinal hemorrhagePulmonary artery stenosisAbnormal umbilical stump bleedingBruising susceptibilityAbnormal bleedingProlonged partial thromboplastin timeReduced protein S activityReduced protein C activityProlonged prothrombin timeReduced factor VII activityReduced factor X activityReduced factor IX activityDecreased level of heparin co-factor IIMenorrhagiaEpistaxisOsteoporosisCutis laxaAngioid streaksIntracranial hemorrhage
Classification & Codes
MeSH Code
C564741Orphanet Code
ORPHA:98434combined vitamin K-dependent clotting factors deficiency
| MeSH | C564741 |
| Orphanet | ORPHA:98434 |
| Treatments | 0 drug(s) |
| Symptoms on record | 31 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO