congenital adrenal hyperplasia due to 11β-hydroxylase deficiency

MeSH: C535978ORPHA: 90795

Overview

medical condition

Available Treatments (0)

No treatments linked yet

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Clinical Presentation

Signs and symptoms associated with congenital adrenal hyperplasia due to 11β-hydroxylase deficiency, sourced from HPO and Orphanet clinical annotations.

Ambiguous genitaliaHypertensionGrowth abnormalityHypokalemiaDecreased circulating renin concentrationAccelerated skeletal maturationDecreased circulating cortisol levelIncreased circulating androstenedione concentrationIncreased circulating androgen concentrationElevated circulating 17-hydroxyprogesterone concentrationIncreased urinary 11-deoxycorticosterone levelLong penisAmbiguous genitalia, femalePrecocious pubertyIrregular menstruationHyperpigmentation of the skinHirsutismAcneIncreased circulating ACTH levelShort statureIsosexual precocious pubertyClitoral hypertrophyPremature pubarchePremature adrenarcheRenal salt wastingPolycystic ovariesGynecomastiaAlopeciaTesticular adrenal rest tumorIncreased serum testosterone levelIntracranial hemorrhagePremature thelarche

Classification & Codes

MeSH Code

C535978

Orphanet Code

ORPHA:90795
congenital adrenal hyperplasia due to 11β-hydroxylase deficiency
MeSHC535978
OrphanetORPHA:90795
Treatments0 drug(s)
Symptoms on record32 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO