congenital diarrhea 5 with tufting enteropathy

MeSH: C567703ORPHA: 92050

Overview

Congenital Tufting Enteropathy is a rare congenital enteropathy presenting with early-onset severe and intractable diarrhea that leads to irreversible intestinal failure

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with congenital diarrhea 5 with tufting enteropathy, sourced from HPO and Orphanet clinical annotations.

Failure to thriveMalabsorptionChronic diarrheaVillous atrophyIrritabilityWeight lossDehydrationSteatorrheaAbdominal distentionSecretory diarrheaAbnormal small intestinal mucosa morphologyElevated fecal osmolalityCataractPhotophobiaAbnormality of the skinArthritisAbnormal large intestinal mucosa morphologyCorneal erosionOrofacial cleftChoanal atresiaOptic disc colobomaVomitingAnal atresiaCholestatic liver diseaseSkeletal dysplasiaPunctate keratitis

Classification & Codes

MeSH Code

C567703

Orphanet Code

ORPHA:92050
congenital diarrhea 5 with tufting enteropathy
MeSHC567703
OrphanetORPHA:92050
Treatments0 drug(s)
Symptoms on record26 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO