congenital osteogenesis imperfecta-microcephaly-cataracts syndrome

MeSH: C537558ORPHA: 2772

Overview

or a few hours after birth. The mode of inheritance appears to be autosomal recessive.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with congenital osteogenesis imperfecta-microcephaly-cataracts syndrome, sourced from HPO and Orphanet clinical annotations.

MicrocephalyCataractIntrauterine growth retardationRecurrent fracturesMicromeliaDisproportionate short-limb short statureHypertelorismBlue scleraeAbnormal rib morphologySingle umbilical arteryVentriculomegalyAbnormality of neuronal migrationDecreased calvarial ossificationCryptorchidismAmbiguous genitaliaVentricular septal defectHypoplastic left ventricleAplasia/Hypoplasia of the cerebellumHypoplasia of penisJoint hypermobilityPosteriorly rotated ears

Classification & Codes

MeSH Code

C537558

Orphanet Code

ORPHA:2772
congenital osteogenesis imperfecta-microcephaly-cataracts syndrome
MeSHC537558
OrphanetORPHA:2772
Treatments0 drug(s)
Symptoms on record21 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
congenital osteogenesis imperfecta-microcephaly-cataracts syndrome | OrphanDrug