congenital stationary night blindness

MeSH: C537743ORPHA: 215

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

night blindness that is characterized by hemeralopia with a moderate loss of visual acuity and caused by defective photoreceptor-to-bipolar cell signaling with common ERG findings of reduced or absent b-waves and generally normal a-waves

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with congenital stationary night blindness, sourced from HPO and Orphanet clinical annotations.

MyopiaNyctalopiaReduced visual acuityAbnormal dark-adapted electroretinogramStrabismusNystagmusEarly-onset non-progressive night blindnessHypermetropiaERG: Reduced dark-adapted b-wave amplitudeReduced amplitude of dark-adapted bright flash electroretinogram a-waveCompensatory head postureColor vision defectAbnormal retinal pigmentationRetinal thinning on OCT

Classification & Codes

MeSH Code

C537743

Orphanet Code

ORPHA:215

congenital stationary night blindness

MeSH	`C537743`
Orphanet	`ORPHA:215`
Treatments	0 drug(s)
Symptoms on record	14 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO