congenital toxoplasmosis

MeSH: D014125ORPHA: 8582 Treatments Available

Overview

toxoplasmosis that involves a reactivated infection of the mother transmitted to the fetus during pregnancy

Available Treatments (2)

DrugFormStatusCountriesLead Time
Pyrimethamine
Orphan
TabletFDA Approved1
Sulfadiazine
TabletFDA Approved1

Clinical Presentation

Signs and symptoms associated with congenital toxoplasmosis, sourced from HPO and Orphanet clinical annotations.

HydrocephalusMicrocephalyHearing impairmentVisual impairmentMicrophthalmiaNystagmusJaundiceSeizureHypotoniaGlobal developmental delayIntrauterine growth retardationFailure to thrive in infancyAscitesPremature birthCardiomegalyThrombocytopeniaAnemiaDiarrheaVentriculomegalyHepatomegalyCerebral calcificationLymphadenopathyElevated circulating hepatic transaminase concentrationAbnormal retinal pigmentationMaculeCognitive impairment

Classification & Codes

MeSH Code

D014125

Orphanet Code

ORPHA:858
congenital toxoplasmosis
MeSHD014125
OrphanetORPHA:858
Treatments2 drug(s)
Symptoms on record26 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO