cranio-osteoarthropathy
ORPHA: 15251 Treatment Available
Overview
Cranio-osteoarthropathy (COA) is a form of primary hypertrophic osteoarthropathy (see this term) characterized by delayed closure of the cranial sutures and fontanels, digital clubbing, arthropathy, and periostosis
Available Treatments (1)
| Drug | Form | Status | Countries | Lead Time |
|---|---|---|---|---|
| celecoxib | oral capsule 50mg, 100mg, 200mg, 400mg | FDA Approved | 10 | 2d |
Clinical Presentation
Signs and symptoms associated with cranio-osteoarthropathy, sourced from HPO and Orphanet clinical annotations.
Large fontanellesAbnormal skull morphologyEczematoid dermatitisMottled pigmentationArthritisJoint swellingJoint stiffnessOsteoarthritisAbnormality of the kneeArthralgiaAbnormal tibia morphologyAbnormal cortical bone morphologyDeviation of fingerClubbing of toes
Classification & Codes
Orphanet Code
ORPHA:1525cranio-osteoarthropathy
| Orphanet | ORPHA:1525 |
| Treatments | 1 drug(s) |
| Symptoms on record | 14 signs |
| Status | published |
Treatment Summary
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO