craniodiaphyseal dysplasia

MeSH: C562940ORPHA: 1513

Overview

osteosclerosis that results in increased calcium concentration located in skull which decreases the size of cranium foramina and cervical spinal canal

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with craniodiaphyseal dysplasia, sourced from HPO and Orphanet clinical annotations.

MacrocephalyCoarse facial featuresStenosis of the external auditory canalConductive hearing impairmentWide nasal bridgeOptic atrophyAbnormal rib morphologyIntellectual disabilityFrontal bossingShort statureCraniofacial hyperostosisDiaphyseal undertubulationDepressed nasal bridge

Classification & Codes

MeSH Code

C562940

Orphanet Code

ORPHA:1513
craniodiaphyseal dysplasia
MeSHC562940
OrphanetORPHA:1513
Treatments0 drug(s)
Symptoms on record13 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
craniodiaphyseal dysplasia | OrphanDrug