craniofacial dysplasia-short stature-ectodermal anomalies-intellectual disability syndrome

ORPHA: 459061

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with craniofacial dysplasia-short stature-ectodermal anomalies-intellectual disability syndrome, sourced from HPO and Orphanet clinical annotations.

Global developmental delayAbnormal facial shapeSparse scalp hairShort statureProminent foreheadSparse eyebrowAbnormality of the kidneyHydrocephalusTrigonocephalyDandy-Walker malformationCerebellar vermis hypoplasiaPes planusHypoplastic toenailsDepressed nasal bridgePosterior fossa cystCamptodactylyInguinal herniaCleft palateBrachycephalyEpicanthusHypertelorismMicrognathiaLow-set earsDownslanted palpebral fissuresWidely spaced teethAnxietyEnuresisSeizureAgenesis of corpus callosumAtrial septal defectAortic valve stenosisTubulointerstitial nephritisSagittal craniosynostosisRelative macrocephalyAttention deficit hyperactivity disorderBilateral single transverse palmar creasesSleep apneaMild hearing impairmentScaphocephalySmall hand

Classification & Codes

Orphanet Code

ORPHA:459061
craniofacial dysplasia-short stature-ectodermal anomalies-intellectual disability syndrome
OrphanetORPHA:459061
Treatments0 drug(s)
Symptoms on record40 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO