cryoglobulinemic vasculitis

MeSH: C565141ORPHA: 91138

Overview

rare multisystem disease characterized by the presence of circulating cryoprecipitable immune complexes in the serum, manifested clinically by a classical triad of purpura, weakness and arthralgia

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with cryoglobulinemic vasculitis, sourced from HPO and Orphanet clinical annotations.

Cutis marmorataPetechiaePurpuraMuscle weaknessFeverVasculitisCirculating immune complexesMediastinal lymphadenopathyCryoglobulinemiaSkin ulcerRenal insufficiencyProteinuriaHematuriaArthritisAbnormality of the liverSplenomegalyAbdominal painHepatomegalyArthralgiaMyalgiaGastrointestinal infarctionsViral hepatitisSensorimotor neuropathyPeripheral neuropathyMononeuropathyGangreneGlomerulopathyKeratoconjunctivitis siccaGastrointestinal hemorrhage

Classification & Codes

MeSH Code

C565141

Orphanet Code

ORPHA:91138
cryoglobulinemic vasculitis
MeSHC565141
OrphanetORPHA:91138
Treatments0 drug(s)
Symptoms on record29 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO