D-glyceric acidemia

MeSH: C535767ORPHA: 941

Overview

genetic disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with D-glyceric acidemia, sourced from HPO and Orphanet clinical annotations.

Loss of consciousnessNonketotic hyperglycinemiaSevere global developmental delayBrain atrophyProfound global developmental delayCerebral visual impairmentMetabolic acidosisProgressive encephalopathyAbnormal circulating enzyme concentration or activityMicrocephalyDelayed speech and language developmentIntellectual disabilitySeizureSpasticityGlobal developmental delayHyperglycinemiaHyperglycinuriaFloppy infantIncreased circulating free fatty acid levelIncreased CSF glycine concentrationProgressive microcephalyHearing impairmentAutistic behaviorMyoclonusChoreaHypoplasia of the corpus callosum

Classification & Codes

MeSH Code

C535767

Orphanet Code

ORPHA:941
D-glyceric acidemia
MeSHC535767
OrphanetORPHA:941
Treatments0 drug(s)
Symptoms on record26 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO