Dejerine–Sottas disease
ICD-10: G60.0ORPHA: 3115
Overview
a rare hereditary neurological disorder characterised by damage to the peripheral nerves and resulting progressive muscle wasting
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Dejerine–Sottas disease, sourced from HPO and Orphanet clinical annotations.
Gait disturbanceNystagmusAreflexiaPes cavusTalipes equinovarusGait ataxiaLimb ataxiaPostural tremorClumsinessUnsteady gaitImpaired vibratory sensationScoliosisKyphoscoliosisDecreased motor nerve conduction velocitySomatic sensory dysfunctionDistal amyotrophyAcute demyelinating polyneuropathySensorimotor neuropathyImpaired pain sensationLower limb muscle weaknessImpaired temperature sensationFrequent fallsUrinary bladder sphincter dysfunctionGenu valgumSkeletal muscle atrophyBabinski signIntrinsic hand muscle atrophy
Classification & Codes
ICD-10 Code
G60.0Orphanet Code
ORPHA:3115Dejerine–Sottas disease
| ICD-10 | G60.0 |
| Orphanet | ORPHA:3115 |
| Treatments | 0 drug(s) |
| Symptoms on record | 27 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO