Desbuquois dysplasia

MeSH: C535943ORPHA: 1425

Overview

osteochondrodysplasia characterized by short stature, joint laxity, scoliosis, and advanced carpal ossification with a delta phalanx

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Desbuquois dysplasia, sourced from HPO and Orphanet clinical annotations.

Joint hypermobilityShort neckGlaucomaProptosisAbnormal metaphysis morphologyIntellectual disabilityBell-shaped thoraxPatellar dislocationAbnormal femoral neck/head morphologySevere short statureDepressed nasal bridgeAccelerated skeletal maturationDisproportionate short-limb short statureAplasia/Hypoplasia of the abdominal wall musculatureCamptodactyly of fingerAbnormal eyelash morphologyBlue scleraeVentricular septal defectScoliosisCoxa valgaCoxa varaGenu recurvatumRadioulnar synostosisElbow dislocationClinodactyly of the 5th fingerSparse hairSmall handAnteverted naresPosteriorly rotated ears

Classification & Codes

MeSH Code

C535943

Orphanet Code

ORPHA:1425
Desbuquois dysplasia
MeSHC535943
OrphanetORPHA:1425
Treatments0 drug(s)
Symptoms on record29 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO