dextro-transposition of the great arteries

ORPHA: 860

Overview

congenital heart disease characterized by complete inversion of the great vessels where the aorta incorrectly arises from the right ventricle and the pulmonary artery incorrectly arises from the left ventricle

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with dextro-transposition of the great arteries, sourced from HPO and Orphanet clinical annotations.

CyanosisTachycardiaCardiac shuntAbnormality of blood circulationAbnormal ventriculoarterial connectionHypoxemiaHeart murmurHyperhidrosisFailure to thriveVentricular septal defectAtrial septal defectAbnormal mitral valve morphologyCongestive heart failureCardiomegalyAbnormal pulmonary valve morphologyPatent ductus arteriosusRight ventricular hypertrophyTachypneaAbnormal coronary artery morphologyAnomalous pulmonary venous returnAbnormal aortic arch morphologyAbnormal QRS complexDextrotransposition of the great arteriesLevotransposition of the great arteriesLeft ventricular outflow tract obstructionBiventricular hypertrophySmall for gestational ageCoarctation of aortaHepatomegalyInterrupted aortic archHypoplastic aortic arch

Classification & Codes

Orphanet Code

ORPHA:860
dextro-transposition of the great arteries
OrphanetORPHA:860
Treatments0 drug(s)
Symptoms on record31 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO