diffuse epidermolytic palmoplantar keratoderma

MeSH: D053546ORPHA: 2199

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with diffuse epidermolytic palmoplantar keratoderma, sourced from HPO and Orphanet clinical annotations.

HyperkeratosisPalmoplantar hyperkeratosisClubbingInterphalangeal joint contracture of fingerAbnormal fingernail morphologyDiffuse palmoplantar hyperkeratosisPalmar hyperkeratosisEpidermal acanthosisKnuckle padHyperhidrosisAbnormal blistering of the skinImpaired temperature sensationImpaired tactile sensationCamptodactylyHypergranulosis

Classification & Codes

MeSH Code

D053546

Orphanet Code

ORPHA:2199
diffuse epidermolytic palmoplantar keratoderma
MeSHD053546
OrphanetORPHA:2199
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO