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distal muscular dystrophy 4

ORPHA: 63273

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

distal muscular dystrophy that has material basis in heterozygous mutation in FLNC on 7q32

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with distal muscular dystrophy 4, sourced from HPO and Orphanet clinical annotations.

Finger flexor weaknessDistal lower limb muscle weaknessIntrinsic hand muscle atrophyDistal upper limb muscle weaknessFoot dorsiflexor weaknessLimited knee flexionHip flexor weaknessGait imbalanceWeakness of facial musculatureExercise-induced myalgiaHyporeflexia of lower limbsAbnormality of the cardiovascular systemInability to walkDifficulty runningFatiguable weakness of proximal limb musclesDecreased finger mobilityProximal lower limb muscle weaknessCardiomyopathyGait disturbance

Classification & Codes

Orphanet Code

ORPHA:63273
distal muscular dystrophy 4
OrphanetORPHA:63273
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO