DOCK8 deficiency

ORPHA: 217390

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with DOCK8 deficiency, sourced from HPO and Orphanet clinical annotations.

Chronic otitis mediaAtopic dermatitisPneumoniaAsthmaRecurrent respiratory infectionsIncreased circulating IgE concentrationRecurrent viral infectionsRecurrent candida infectionsDecreased total T cell countRecurrent bacterial skin infectionsDecreased total B cell countRecurrent sinusitisOnychomycosisSkin ulcerVerrucaeSquamous cell carcinomaAnal canal squamous carcinomaSquamous cell carcinoma of the vulva

Classification & Codes

Orphanet Code

ORPHA:217390
DOCK8 deficiency
OrphanetORPHA:217390
Treatments0 drug(s)
Symptoms on record18 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO