Donnai-Barrow syndrome

MeSH: C536390ORPHA: 2143

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Donnai-Barrow syndrome, sourced from HPO and Orphanet clinical annotations.

ProteinuriaAbnormality of the uterusMacrocephalyWide anterior fontanelHypertelorismBroad foreheadWidow's peakPosteriorly rotated earsSensorineural hearing impairmentDownslanted palpebral fissuresProptosisProgressive visual lossRetinal detachmentMyopiaRetinal dystrophyIris colobomaCongenital diaphragmatic herniaBicornuate uterusIntellectual disabilitySeizureGlobal developmental delayUmbilical herniaOmphaloceleVentricular septal defectIntestinal malrotationShort noseDepressed nasal bridgeAplasia/Hypoplasia of the corpus callosum

Classification & Codes

MeSH Code

C536390

Orphanet Code

ORPHA:2143
Donnai-Barrow syndrome
MeSHC536390
OrphanetORPHA:2143
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO