Dowling-Degos disease
MeSH: C562924ORPHA: 79145
Overview
pigmentation disease characterized by a reticulate pattern of abnormally dark skin coloring, particularly in the body's folds and creases
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Dowling-Degos disease, sourced from HPO and Orphanet clinical annotations.
Progressive reticulate hyperpigmentationAbnormality of the neckHyperkeratosisInguinal frecklingPruritusHypermelanotic maculeAbnormality of the handAbnormal fingernail morphologyHeat intoleranceScrotal hyperpigmentationHyperpigmented papuleErythematous papuleDigital pitting scarPenile frecklingAcne inversaHyperkeratotic papuleArthritisMixed hypo- and hyperpigmentation of the skinPalmar pitsGeneralized abnormality of skinHypopigmented maculeAnal margin squamous cell carcinomaKeratoacanthomaSkin vesicleEpidermoid cyst
Classification & Codes
MeSH Code
C562924Orphanet Code
ORPHA:79145Dowling-Degos disease
| MeSH | C562924 |
| Orphanet | ORPHA:79145 |
| Treatments | 0 drug(s) |
| Symptoms on record | 25 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO