Dravet syndrome

ORPHA: 33069

Overview

epilepsy characterized by frequent febrile seizures and with onset before 1 year

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Dravet syndrome, sourced from HPO and Orphanet clinical annotations.

Developmental regressionProgressive gait ataxiaFocal-onset seizureLimited neck range of motionAutistic behaviorAnxietyParkinsonismPhotosensitive myoclonic seizureMyoclonusRigidityBradykinesiaGeneralized myoclonic seizureFocal aware seizureFebrile seizure (within the age range of 3 months to 6 years)Focal impaired awareness seizureCogwheel rigidityFocal hemiclonic seizurePhotosensitive tonic-clonic seizureAtypical absence seizureObsessive-compulsive traitMultifocal epileptiform dischargesGeneralized clonic seizureComplex febrile seizureInterictal epileptiform activityFacial ticsEpilepsia partialis continuaCognitive impairmentShort attention spanPallorPes planusGlobal brain atrophyDroolingIncoordinationAction tremorLimited knee extensionPoor fine motor coordinationPes valgusFloppy infantEEG with focal epileptiform dischargesEEG with generalized epileptiform dischargesDysgenesis of the hippocampusStatus epilepticus without prominent motor symptomsTibial torsionImpulsivityCyanotic episodeGeneralized tonic seizure

Classification & Codes

Orphanet Code

ORPHA:33069
Dravet syndrome
OrphanetORPHA:33069
Treatments0 drug(s)
Symptoms on record46 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO