drug reaction with eosinophilia and systemic symptoms

MeSH: D063926ORPHA: 139402

Overview

drug eruption characterized by high fever, erythematous rash and inflammation of internal organs

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with drug reaction with eosinophilia and systemic symptoms, sourced from HPO and Orphanet clinical annotations.

Renal insufficiencyNephrotic syndromeSkin rashErythrodermaCardiac arrestWeight lossIncreased total eosinophil countFeverTubulointerstitial nephritisDyspneaPulmonary infiltratesInfectious encephalitisLymphadenopathyElevated circulating hepatic transaminase concentrationInterstitial pneumonitisAcute hepatic failurePeripheral neuropathyErythemaHepatitisMaculeCoughMyocarditisEnanthemaImmunologic hypersensitivityThyroiditisAngioedemaIncreased total lymphocyte countPustule

Classification & Codes

MeSH Code

D063926

Orphanet Code

ORPHA:139402
drug reaction with eosinophilia and systemic symptoms
MeSHD063926
OrphanetORPHA:139402
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO