dystonia-aphonia syndrome

ORPHA: 412217

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with dystonia-aphonia syndrome, sourced from HPO and Orphanet clinical annotations.

Tongue muscle weaknessDysarthriaGait disturbanceDysphoniaDysphagiaImpaired masticationGeneralized dystoniaMacroglossiaSeizureCerebellar atrophyCerebral atrophyUnsteady gaitAnarthriaMixed demyelinating and axonal polyneuropathySlowed horizontal saccadesAbnormal vocal cord morphologyOromandibular dystoniaAbnormal mitochondrial shapeAbnormal urinary odorGingival overgrowthAnxietyGlobal developmental delayMyoclonusCognitive impairment

Classification & Codes

Orphanet Code

ORPHA:412217
dystonia-aphonia syndrome
OrphanetORPHA:412217
Treatments0 drug(s)
Symptoms on record24 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO