ectopic Cushing syndrome

MeSH: D000182ORPHA: 99889

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with ectopic Cushing syndrome, sourced from HPO and Orphanet clinical annotations.

Diabetes mellitusIncreased circulating cortisol levelIncreased circulating ACTH levelParadoxical increased cortisol secretion on dexamethasone suppression testIncreased urinary cortisol levelFatiguable weakness of proximal limb musclesAmenorrheaAtypical behaviorEmotional labilityAnxietyHypertensionOsteoporosisHyperpigmentation of the skinThin skinBruising susceptibilityHirsutismPlethoraPoor wound healingAcneStriae distensaeMuscle weaknessAbnormality of the cardiovascular systemDecreased total lymphocyte countTruncal obesityIncreased total leukocyte countImmunodeficiencyIncreased body weightProximal amyotrophyAdrenal hyperplasiaIntra-oral hyperpigmentationAbdominal obesityCapillary fragilityDorsocervical fat padAstheniaIncreased circulating androgen concentrationEcchymosisAbnormal libidoDecreased total eosinophil countInsomniaMoon faciesDepressionPsychotic episodesSecondary amenorrheaOligomenorrheaPurpuraStrokeMyocardial infarctionWeight lossDiarrheaAnorexiaAbnormality of the respiratory systemSparse scalp hairMemory impairmentAbnormal lymph node morphologyVertebral compression fractureMalignant gastrointestinal tract tumorsRecurrent cutaneous fungal infectionsPeripheral edemaPancreatic endocrine tumorAtypical pulmonary carcinoid tumorFlushingSuicidal ideationImpaired glucose toleranceNeoplasm of the thymusNeuroendocrine neoplasmSkin ulcerPsychosisDementiaPheochromocytomaMedullary thyroid carcinomaSmall intestine carcinoidPancreatic adenocarcinomaNeoplasm of the stomachPedal edemaParanoiaProstate cancerPanic attackSmall cell lung carcinomaPulmonary carcinoid tumorPancreatoblastomaHypergastrinemia

Classification & Codes

MeSH Code

D000182

Orphanet Code

ORPHA:99889

ectopic Cushing syndrome

MeSH	`D000182`
Orphanet	`ORPHA:99889`
Treatments	0 drug(s)
Symptoms on record	81 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO