encephalopathy due to sulfite oxidase deficiency

ORPHA: 833

Overview

Encephalopathy due to sulfite oxidase deficiency is a rare neurometabolic disorder characterized by seizures, progressive encephalopathy and lens dislocation

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with encephalopathy due to sulfite oxidase deficiency, sourced from HPO and Orphanet clinical annotations.

MicrocephalyFull cheeksLong philtrumDeeply set eyeMyopiaEctopia lentisSeizureAtaxiaSpasticitySpastic tetraparesisNausea and vomitingDevelopmental regressionAbnormal pattern of respirationShort noseAminoaciduriaHemiplegia/hemiparesisFeeding difficulties in infancySevere intellectual disabilityProminent foreheadThick vermilion borderAbnormality of movement

Classification & Codes

Orphanet Code

ORPHA:833
encephalopathy due to sulfite oxidase deficiency
OrphanetORPHA:833
Treatments0 drug(s)
Symptoms on record21 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO