epidermolysis bullosa simplex with mottled pigmentation

MeSH: C535959ORPHA: 79397

Overview

Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a basal subtype of epidermolysis bullosa simplex (EBS, see this term) characterized by generalized blistering with mottled or reticulate brown pigmentation

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with epidermolysis bullosa simplex with mottled pigmentation, sourced from HPO and Orphanet clinical annotations.

Mottled pigmentationLamina lucida cleavageReticulated skin pigmentationSkin fragility with non-scarring blisteringAbnormal blistering of the skinMixed hypo- and hyperpigmentation of the skinHypermelanotic maculeNail dysplasiaSpotty hypopigmentationPlantar hyperkeratosisNail dystrophyHypomelanotic maculePalmar hyperkeratosisHyperkeratotic papuleAbnormality of the dentitionCutaneous photosensitivityMiliaAlopeciaOral mucosal blisters

Classification & Codes

MeSH Code

C535959

Orphanet Code

ORPHA:79397
epidermolysis bullosa simplex with mottled pigmentation
MeSHC535959
OrphanetORPHA:79397
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO