exercise-induced malignant hyperthermia

ORPHA: 466650

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with exercise-induced malignant hyperthermia, sourced from HPO and Orphanet clinical annotations.

Abnormality of the nervous systemMalignant hyperthermiaNauseaHeadacheVertigoTachypneaSinus tachycardiaFatigueAbnormal pulse pressureSeizureAtaxiaLethargyConfusionMuscle weaknessDecreased liver functionProlonged QT intervalAbnormal bleedingVomitingHyperkalemiaHypotensionHypocalcemiaHyperphosphatemiaLactic acidosisElevated circulating creatine kinase concentrationAbnormality of the coagulation cascadeExercise-induced muscle crampsAbnormal T-waveST segment depressionHypocapniaCracklesDeliriumFlushingOliguriaDry skinAnhidrosisHepatic failureThrombocytopeniaAcute kidney injuryHepatic encephalopathyRhabdomyolysisDisseminated intravascular coagulation

Classification & Codes

Orphanet Code

ORPHA:466650
exercise-induced malignant hyperthermia
OrphanetORPHA:466650
Treatments0 drug(s)
Symptoms on record41 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO