familial partial lipodystrophy

MeSH: D052496ORPHA: 79083

Overview

lipodystrophy characterized by abnormal subcutaneous adipose tissue distribution beginning in late childhood or early adult life

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with familial partial lipodystrophy, sourced from HPO and Orphanet clinical annotations.

HypertensionInsulin resistanceLipoatrophyDiabetes mellitusInsulin-resistant diabetes mellitusXanthomatosisHypertriglyceridemiaHepatomegalyLoss of subcutaneous adipose tissue in limbsAplasia/Hypoplasia of the skinSecondary amenorrheaThin skinAtherosclerosisSkeletal muscle hypertrophyPolycystic ovariesLoss of facial adipose tissueOligomenorrheaAcanthosis nigricansHepatic steatosisCongestive heart failureHypertrophic cardiomyopathyCoronary artery atherosclerosisPancreatitisSplenomegalyHyperuricemiaGeneralized hirsutismMyopathyMyalgiaCalf muscle pseudohypertrophyAbnormality of skeletal muscle fiber sizeDysmenorrheaPrimary amenorrheaCirrhosisProminent veins on trunk

Classification & Codes

MeSH Code

D052496

Orphanet Code

ORPHA:79083
familial partial lipodystrophy
MeSHD052496
OrphanetORPHA:79083
Treatments0 drug(s)
Symptoms on record34 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO