familial partial lipodystrophy type 5

ORPHA: 435651

Overview

familial partial lipodystrophy characterized by autosomal recessive inheritance that has material basis in mutation in the CIDEC gene on chromosome 3p25

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with familial partial lipodystrophy type 5, sourced from HPO and Orphanet clinical annotations.

Loss of subcutaneous adipose tissue in limbsLipodystrophyPolycystic ovariesInsulin-resistant diabetes mellitusOligomenorrheaAcanthosis nigricansHepatic steatosisPancreatitisHypertriglyceridemiaHepatomegalyDecreased serum leptinSkeletal muscle hypertrophyCalf muscle hypertrophyLoss of gluteal subcutaneous adipose tissueDecreased adiponectin level

Classification & Codes

Orphanet Code

ORPHA:435651
familial partial lipodystrophy type 5
OrphanetORPHA:435651
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO