familial temporal lobe epilepsy 7

ORPHA: 101046

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

temporal lobe epilepsy characterized by autosomal dominant inheritance of focal seizures with prominent auditory symptoms and that has material basis in heterozygous mutation in the RELN gene on chromosome 7q22

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with familial temporal lobe epilepsy 7, sourced from HPO and Orphanet clinical annotations.

Focal-onset seizureAuditory hallucinationEEG with focal epileptiform dischargesAphasiaInterictal epileptiform activityFocal aware seizureVisual hallucinationFocal autonomic seizureAbnormal autonomic nervous system physiologyNocturnal seizuresAtypical behaviorDepressionBilateral tonic-clonic seizureMigraineGeneralized-onset seizureBilateral tonic-clonic seizure with focal onsetImpulsivity

Classification & Codes

Orphanet Code

ORPHA:101046

familial temporal lobe epilepsy 7

Orphanet	`ORPHA:101046`
Treatments	0 drug(s)
Symptoms on record	17 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO