Fanconi syndrome

MeSH: D005198ORPHA: 3337

Overview

renal tubular transport disease of the proximal renal tubes characterized by glucosuria, phosphaturia, generalized aminoaciduria and HCO3 wasting

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Fanconi syndrome, sourced from HPO and Orphanet clinical annotations.

Renal phosphate wastingGrowth delayProximal renal tubular acidosisGeneralized aminoaciduriaGlycosuriaLow-molecular-weight proteinuriaHyperuricosuriaBicarbonaturiaBicarbonate-wasting renal tubular acidosisHyperchloremic metabolic acidosisAbnormal urine pHMuscle weaknessWeight lossHypophosphatemiaBone painIncreased susceptibility to fracturesOsteomalaciaHypokalemiaIncreased urinary potassiumDecreased circulating carnitine concentrationHypouricemiaHypophosphatemic ricketsRenal sodium wastingChronic kidney diseaseDehydrationHypercalciuriaStage 5 chronic kidney diseaseHypoglycemiaPulmonary fibrosis

Classification & Codes

MeSH Code

D005198

Orphanet Code

ORPHA:3337
Fanconi syndrome
MeSHD005198
OrphanetORPHA:3337
Treatments0 drug(s)
Symptoms on record29 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO