FBLN1-related developmental delay-central nervous system anomaly-syndactyly syndrome

ORPHA: 404451

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with FBLN1-related developmental delay-central nervous system anomaly-syndactyly syndrome, sourced from HPO and Orphanet clinical annotations.

CryptorchidismMacular degenerationDelayed speech and language developmentSyndactylyDysarthriaMotor delaySpastic tetraparesisDystoniaCerebral cortical atrophyPseudobulbar signsDroolingModerate intellectual disabilitySyringomyeliaNonprogressive encephalopathyCongenital bilateral hip dislocationChoroidal neovascularizationInfantile spasmsDelayed ability to walk

Classification & Codes

Orphanet Code

ORPHA:404451
FBLN1-related developmental delay-central nervous system anomaly-syndactyly syndrome
OrphanetORPHA:404451
Treatments0 drug(s)
Symptoms on record18 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO