frontonasal dysplasia with alopecia and genital anomaly

ORPHA: 228390

Overview

Frontonasal dysplasia with alopecia and genital anomaly is a new phenotype of frontonasal dysplasia associated with total alopecia and hypogonadism

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with frontonasal dysplasia with alopecia and genital anomaly, sourced from HPO and Orphanet clinical annotations.

CryptorchidismSmall scrotumHypogonadismAbnormality of the dentitionBrachycephalyBroad philtrumHypertelorismLow-set earsUnderdeveloped nasal alaeAnteverted naresStrabismusTelecanthusMicrophthalmiaUpslanted palpebral fissureNystagmusConical toothMild intellectual disabilityAgenesis of corpus callosumCalvarial skull defectIntrauterine growth retardationOligohydramniosAlopeciaFrontal bossingEncephaloceleFine hairAgenesis of cerebellar vermisModerate intellectual disabilityCoronal craniosynostosisDepressed nasal bridgeBifid nose

Classification & Codes

Orphanet Code

ORPHA:228390
frontonasal dysplasia with alopecia and genital anomaly
OrphanetORPHA:228390
Treatments0 drug(s)
Symptoms on record30 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO