gamma heavy chain disease

ORPHA: 100026

Overview

heavy chain disease that results from an overproduction of gamma antibody (IgG)

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with gamma heavy chain disease, sourced from HPO and Orphanet clinical annotations.

Abnormal palate morphologySkin rashRheumatoid arthritisSplenomegalyThrombocytopeniaAutoimmune hemolytic anemiaAnemiaFeverAutoimmune thrombocytopeniaDysphagiaRecurrent respiratory infectionsHepatomegalyLymphadenopathyOsteolysisAutoimmunityAbnormal lymphocyte morphologyAbnormal bone marrow cell morphologyPeripheral neuropathyFatigueNeoplasm of the tongue

Classification & Codes

Orphanet Code

ORPHA:100026
gamma heavy chain disease
OrphanetORPHA:100026
Treatments0 drug(s)
Symptoms on record20 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
gamma heavy chain disease | OrphanDrug