global developmental delay-neuro-ophthalmological abnormalities-seizures-intellectual disability syndrome

ORPHA: 488613

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with global developmental delay-neuro-ophthalmological abnormalities-seizures-intellectual disability syndrome, sourced from HPO and Orphanet clinical annotations.

Developmental regressionFocal impaired awareness seizureLimb hypertoniaInability to walkImpaired smooth pursuitFloppy infantEEG with generalized epileptiform dischargesCerebral visual impairmentOverfolded helixPectus excavatumPolymicrogyriaDelayed myelinationGlobal developmental delayGeneralized hypotoniaIntellectual disabilitySeizureFailure to thriveGrowth delayEEG abnormalityExpressive language delayMultifocal epileptiform dischargesFeeding difficultiesHydronephrosisCleft palateHigh palateStrabismusNystagmusBilateral tonic-clonic seizure

Classification & Codes

Orphanet Code

ORPHA:488613
global developmental delay-neuro-ophthalmological abnormalities-seizures-intellectual disability syndrome
OrphanetORPHA:488613
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
global developmental delay-neuro-ophthalmological abnormalities-seizures-intellectual disability syndrome | OrphanDrug