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Gorlin-Chaudhry-Moss syndrome

MeSH: C537290ORPHA: 2095

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

Gorlin-Chaudhry-Moss (GCM) syndrome is a multiple congenital anomaly syndrome characterized by craniofacial dysostosis, facial dysmorphism, conductive hearing loss, generalized hypertrichosis, and extremity, ocular and dental anomalies

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Gorlin-Chaudhry-Moss syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormality of the dentitionBrachycephalyLow anterior hairlineHypertelorismConductive hearing impairmentAbnormality of the eyeAbnormal eyelid morphologyAbnormality of visionNystagmusOligodontiaAbnormal foot morphologyCoarse hairGeneralized hirsutismShort statureCoronal craniosynostosisAbnormal metacarpal morphologyCongenital craniofacial dysostosisShort distal phalanx of fingerUnderdeveloped supraorbital ridgesHypoplasia of the maxillaAstigmatismSclerocorneaAbnormal skull morphologyUmbilical herniaPatent ductus arteriosusAplasia/Hypoplasia of the nasal boneUpper eyelid colobomaMild intellectual disability

Classification & Codes

MeSH Code

C537290

Orphanet Code

ORPHA:2095
Gorlin-Chaudhry-Moss syndrome
MeSHC537290
OrphanetORPHA:2095
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO