granulomatosis with polyangiitis

MeSH: D014890ORPHA: 900

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

wegner granulomatosis

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with granulomatosis with polyangiitis, sourced from HPO and Orphanet clinical annotations.

Abnormal oral cavity morphologySinusitisAbnormality of the noseOtitis mediaEpistaxisHematuriaWeight lossFeverPulmonary infiltratesRecurrent respiratory infectionsVasculitisCerebral ischemiaArthralgiaGranulomatosisAutoimmunityFatigueGlomerulopathyProteinuriaGlomerulonephritisNasolacrimal duct obstructionAbnormality of the hypothalamus-pituitary axisSkin rashArthritisNausea and vomitingAbdominal painRespiratory insufficiencyHemoptysisPulmonary fibrosisElevated erythrocyte sedimentation ratePolyarticular arthritisChronic pulmonary obstructionRecurrent intrapulmonary hemorrhagePeripheral neuropathyElevated circulating C-reactive protein concentrationIncreased inflammatory responseCoughCytoplasmic antineutrophil antibody positivityAnti-proteinase 3 antibody positivityAnti-myeloperoxidase antibody positivityAnti-neutrophil elastase antibody positivityScleritisInflammatory abnormality of the eyePeriorbital edemaChest painPapuleProstatitisUreteral stenosisRenal insufficiencyHydronephrosisChronic otitis mediaSensorineural hearing impairmentRetinopathyKeratitisVisual impairmentProptosisSensory neuropathyHypertensionDiabetes insipidusPurpuraSeizureMeningitisSubglottic stenosisAngina pectorisPericarditisPancreatitisRestrictive ventilatory defectPleuritisPleural effusionGastrointestinal hemorrhageHemiplegiaHeadacheMyalgiaVenous thrombosisIntestinal obstructionCranial nerve paralysisArrhythmiaDiffuse alveolar hemorrhagePulmonary noduleGangreneSkin ulcer

Classification & Codes

MeSH Code

D014890

Orphanet Code

ORPHA:900

granulomatosis with polyangiitis

MeSH	`D014890`
Orphanet	`ORPHA:900`
Treatments	0 drug(s)
Symptoms on record	80 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO