Grubben-de Cock-Borghgraef syndrome

MeSH: C537621ORPHA: 2101

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Grubben-de Cock-Borghgraef syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormality of the dentitionRound faceShort neckAbnormality of eye movementBlue scleraeDelayed speech and language developmentDry skinEczematoid dermatitisSeizureHypotoniaGlobal developmental delayReduced tendon reflexesPartial agenesis of the corpus callosumDeviation of fingerSmall hand

Classification & Codes

MeSH Code

C537621

Orphanet Code

ORPHA:2101
Grubben-de Cock-Borghgraef syndrome
MeSHC537621
OrphanetORPHA:2101
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
Grubben-de Cock-Borghgraef syndrome | OrphanDrug