Heimler syndrome 1

ORPHA: 3220

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Heimler syndrome 1, sourced from HPO and Orphanet clinical annotations.

Abnormal fingernail morphologyIntellectual disabilityExternal genital hypoplasiaPili tortiAbnormal toenail morphologyAbnormal hair quantityThin eyebrowAbnormality of nail colorRound facePrimary amenorrheaLarge handsShort statureArrhythmiaSensory neuropathyAcanthosis nigricansHyporeflexiaCerebral calcificationDelayed skeletal maturationIchthyosisPeripheral neuropathyHigh anterior hairlineMuscle flaccidityCamptodactyly of fingerHypogonadismAbnormality of the dentitionHearing impairmentSensorineural hearing impairmentAbnormal eyelid morphologyAbnormal eyebrow morphologyAbnormal nasolacrimal system morphologyTaurodontiaAbnormal dental enamel morphologyDiabetes mellitus

Classification & Codes

Orphanet Code

ORPHA:3220
Heimler syndrome 1
OrphanetORPHA:3220
Treatments0 drug(s)
Symptoms on record33 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO