hemoglobin D disease

ORPHA: 900391 Treatment Available

Overview

Human disease

Available Treatments (1)

DrugFormStatusCountriesLead Time
Crizanlizumab
Orphan Cold Chain
IV infusion, 5mg/mLFDA Approved314d

Clinical Presentation

Signs and symptoms associated with hemoglobin D disease, sourced from HPO and Orphanet clinical annotations.

Imbalanced hemoglobin synthesisAbnormal hemoglobinReduced hemoglobin AReduced beta/alpha synthesis ratioReduced alpha/beta synthesis ratioDecreased mean corpuscular volumeDecreased mean corpuscular hemoglobin concentrationIncreased HbA2 hemoglobinSickled erythrocytesHbS hemoglobinPallorSplenomegalyAnemiaAbdominal pain

Classification & Codes

Orphanet Code

ORPHA:90039
hemoglobin D disease
OrphanetORPHA:90039
Treatments1 drug(s)
Symptoms on record14 signs
Statuspublished

Treatment Summary

Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO