hemophagocytic syndrome associated with an infection
ORPHA: 158048
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hemophagocytic syndrome associated with an infection, sourced from HPO and Orphanet clinical annotations.
HemophagocytosisSplenomegalyPancytopeniaFeverAbnormal inflammatory responseAbnormal T cell subset distributionAbnormal cytokine signalingSevere viral infectionSevere infectionAbnormality of the nervous systemThrombocytopeniaDecreased total neutrophil countAnemiaHypertriglyceridemiaHepatomegalyElevated circulating hepatic transaminase concentrationIncreased circulating ferritin concentrationDisseminated intravascular coagulationHypofibrinogenemiaChronic active Epstein-Barr virus infectionAbnormal total natural killer cell countSeizureAtaxiaDysarthriaHyperproteinemiaCranial nerve paralysisCSF pleocytosisInvasive fungal infectionPeriventricular white matter hyperintensitiesNuchal rigiditySevere cytomegalovirus infectionOpportunistic bacterial infectionEncephalopathyInvasive parasitic infectionHistoplasmosis
Classification & Codes
Orphanet Code
ORPHA:158048hemophagocytic syndrome associated with an infection
| Orphanet | ORPHA:158048 |
| Treatments | 0 drug(s) |
| Symptoms on record | 35 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO