Hennekam syndrome
MeSH: C537255ORPHA: 2136
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Hennekam syndrome, sourced from HPO and Orphanet clinical annotations.
HypertelorismLow-set earsWide nasal bridgeDelayed eruption of teethLymphedemaIntellectual disabilityMild postnatal growth retardationDecreased total lymphocyte countAbnormal facial shapeMalabsorptionDecreased circulating immunoglobulin concentrationDepressed nasal bridgeAbnormal dental morphologyTooth agenesisSupernumerary toothFlat faceLymphangiomaGingival overgrowthEpicanthusBroad foreheadGlaucomaNarrow chestErysipelasSeizureAscitesSplenomegalyRecurrent respiratory infectionsLymphadenopathyAbnormal oral mucosa morphologyHorseshoe kidneyEctopic kidneyNarrow mouthRetrognathiaShort philtrumConductive hearing impairmentPachygyriaCraniosynostosisPericardial effusionAbnormal foot morphologyHydrops fetalisPyloric stenosisRespiratory insufficiencySparse axillary hairHypocalcemiaFinger syndactylyPulmonary lymphangiectasiaChylothoraxArteriovenous malformationCamptodactyly of fingerBenign neoplasm of the central nervous systemAbnormal pinna morphology
Classification & Codes
MeSH Code
C537255Orphanet Code
ORPHA:2136Hennekam syndrome
| MeSH | C537255 |
| Orphanet | ORPHA:2136 |
| Treatments | 0 drug(s) |
| Symptoms on record | 51 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO