hereditary ATTR amyloidosis
ORPHA: 271861
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary ATTR amyloidosis, sourced from HPO and Orphanet clinical annotations.
ConstipationGastroparesisSkeletal muscle atrophyOrthostatic hypotension due to autonomic dysfunctionSensorimotor neuropathyArrhythmiaConstrictive median neuropathyAbnormal autonomic nervous system physiologyHeart blockCardiac transthyretin amyloid depositionVitreous floatersRenal insufficiencyNephrotic syndromeMuscle weaknessWeight lossLumbar spinal canal stenosisFoot dorsiflexor weaknessImpaired temperature sensationCerebral amyloid angiopathyPainAbnormal pupil shapeAcroparesthesiaWrist dropHypoesthesiaTendon ruptureUrinary retentionNephropathyGlaucomaImpotenceAnhidrosisKeratoconjunctivitis siccaCongestive heart failureLeft ventricular hypertrophyRestrictive cardiomyopathyDiarrheaNausea and vomiting
Classification & Codes
Orphanet Code
ORPHA:271861hereditary ATTR amyloidosis
| Orphanet | ORPHA:271861 |
| Treatments | 0 drug(s) |
| Symptoms on record | 36 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO