Hereditary Leiomyomatosis and Renal Cell Cancer

ICD-10: 2B60.ZMeSH: D052159

Overview

An inherited cancer syndrome characterized by cutaneous leiomyomas, uterine fibroids, and aggressive renal cell carcinomas. Caused by mutations in the FH gene encoding fumarate hydratase. Affects approximately 1 in 200,000 individuals and requires regular cancer surveillance.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Classification & Codes

ICD-10 Code

2B60.Z

MeSH Code

D052159
Hereditary Leiomyomatosis and Renal Cell Cancer
ICD-102B60.Z
MeSHD052159
Treatments0 drug(s)
Statuspublished
Factual Authority
Last Updated3/21/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO