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hereditary leiomyomatosis and renal cell cancer syndrome

ICD-10: D23MeSH: C535516ORPHA: 523

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a hereditary cancer syndrome characterized by a predisposition to cutaneous and uterine leiomyomas and, in some families, to renal cell cancer

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with hereditary leiomyomatosis and renal cell cancer syndrome, sourced from HPO and Orphanet clinical annotations.

Uterine leiomyomaCataractPruritusUterine leiomyosarcomaAbnormality of the musculaturePapillary renal cell carcinoma type 2Multiple cutaneous leiomyomasCutaneous leiomyomaBarrett esophagusVaginal neoplasmEsophageal neoplasm

Classification & Codes

ICD-10 Code

D23

MeSH Code

C535516

Orphanet Code

ORPHA:523
hereditary leiomyomatosis and renal cell cancer syndrome
ICD-10D23
MeSHC535516
OrphanetORPHA:523
Treatments0 drug(s)
Symptoms on record11 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO