hereditary sensory and autonomic neuropathy type 2

ORPHA: 970

Overview

hereditary sensory neuropathy characterized by progressively reduced sensation to pain, temperature, and touch, loss of myelinated and unmyelinated fibers, and hypotonia with onset at birth or in early childhood

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with hereditary sensory and autonomic neuropathy type 2, sourced from HPO and Orphanet clinical annotations.

HyperhidrosisTapered fingerDystrophic toenailFoot acroosteolysisWormian bonesOsteolysisAbnormality of the kneeAbnormality of the ankleAbnormal cortical bone morphologySkeletal muscle atrophyAbnormal hip bone morphologyHyperlordosisReduced bone mineral densityAbnormal epiphysis morphologyDystrophic fingernails

Classification & Codes

Orphanet Code

ORPHA:970
hereditary sensory and autonomic neuropathy type 2
OrphanetORPHA:970
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO