hereditary sensory and autonomic neuropathy with spastic paraplegia
MeSH: C564948ORPHA: 139578
Overview
This syndrome is characterized by the association of an axonal sensory and autonomic neuropathy with spastic paraplegia
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary sensory and autonomic neuropathy with spastic paraplegia, sourced from HPO and Orphanet clinical annotations.
Acral ulcerationSpasticitySpastic paraplegiaGait disturbanceHyperreflexiaDistal sensory impairment of all modalitiesImpaired pain sensationPeripheral neuropathyAbnormal autonomic nervous system physiologySkin ulcerAbnormal spinal cord morphologyClonusSensory axonal neuropathyDecreased motor nerve conduction velocityBabinski signDistal amyotrophyProgressive spastic paraplegiaFoot osteomyelitis
Classification & Codes
MeSH Code
C564948Orphanet Code
ORPHA:139578hereditary sensory and autonomic neuropathy with spastic paraplegia
| MeSH | C564948 |
| Orphanet | ORPHA:139578 |
| Treatments | 0 drug(s) |
| Symptoms on record | 18 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO